Cancer Treatment Archives - NFCR

Cancer Treatment

Ricardo Garcia: The Power of Repurposing

When volasertib was discontinued after an unsatisfactory Phase III clinical trial as an anti-leukemia drug, it did not die a quick death, or die at all. Like Viagra and thalidomide before it, volasertib was “repurposed;” if the original vision for the compound fails, it is simply a matter of finding…...

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Wei Zhang: The Art of Precision

“The essence of precision medicine, in particular precision oncology, is to make cancer management more precise based on genomic mapping and molecular characterization of the unique tumors for each patient,” says Dr. Wei Zhang. “The cancer management that needs to be precision include diagnosis, prognosis, treatment plan, treatment monitoring, and…...

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New Combination Therapy Improves Pancreatic Cancer Survival

A new combination of two standing drugs and radiation therapy has the potential to revolutionize the treatment and care of pancreatic cancer, one of the most lethal diagnoses an oncologist can face with patients. Using data from studies by NFCR fellow Dr. Rakesh Jain, investigators at Massachusetts General Hospital used…...

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“Pink Drink” to Aid Brain Tumor Treatment

Approved in June 2017 by the U.S. Food and Drug Administration and launched commercially in-country in October 2018, 5-Aminolevulinic Acid (also known as 5-ALA, and composed of aminolevulinic acid hydrochloride) is an optical imaging agent for use in patients with high-grade gliomas. Nicknamed the “pink drink,” 5-ALA is a surgical…...

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Hormone Therapy: Influencing Breast Cancer Treatment and Beyond

While recent medical discoveries, from drugs to imaging techniques, continue to revolutionize cancer care, none of them would be possible without foundations having been laid years, or even decades, earlier. Groundbreaking work by the late endocrinologist Jack Gorski, Ph.D., who passed away in 2006 and was funded by the National…...

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Artemisinin Therapies: Connecting the Dots

You wouldn’t think it, but the science cannot be denied: One of the newest and most promising drug candidates for cancer was actually developed all the way back in 1972. For malaria. “There were some hints in the literature, but we were totally ignorant,” admits Curt Civin, M.D., whose work…...

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Brain Cancer Surgery: Thriving in Recovery

Brain cancer is a formidable adversary in the world of oncology. Against substantial odds, patients work with dedicated doctors to mount a counter offensive. The road to recovery is, to no one’s astonishment, arduous, as brain surgery exposes the very epicenter of our being, behavior, personality, motor skills and memory.…...

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