Cancer Types | Brain Cancer - National Foundation for Cancer Research

Brain Cancer

Brain Cancer

About Brain Cancer

People of all ages are diagnosed with brain cancer, but there is more frequency among children and older adults. Brain cancer is the second most commonly diagnosed cancer in children (after leukemia).

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Prevention Tips

  • Limiting radiation exposure as much as possible.

According to the American Cancer Society (ACS), there are no known lifestyle-related or environmental risk factors for brain and spinal cord tumors, so at this time there is no known way to protect against most of these tumors. However, an overall healthy lifestyle such as quitting smoking, a healthy diet, and physical activities can help reduce the overall risk of getting cancers.

Resource: Can Brain and Spinal Cord Tumors in Adults Be Prevented? | American Cancer Society

 

Brain Cancer Signs & Symptoms

  • Headaches
  • Seizures
  • Difficulty thinking and/or speaking
  • Changes in personality
  • Loss of balance
  • Change in vision including blurriness, double vision, abnormal eye movements, light sensitivity, and loss of vision
  • Memory loss
  • Disorientation
  • Fatigue and muscle weakness
  • Muscle weakness
  • Depression
  • Anxiety
  • Tingling or stiffness on one side of the body

Source: National Brain Tumor Society 2024

Risk Factors for Brain Cancer

  • Radiation exposure
  • Family history
    • Neurofibromatosis type 1 (NF1)
    • Neurofibromatosis type 2 (NF2)
    • Tuberous sclerosis
    • Von Hippel-Lindau syndrome
    • Li-Fraumeni syndrome
    • Turcot syndrome
    • Other syndromes – Gorlin syndrome (basal cell nevus syndrome); Cowden syndrome
  • Weakened immune system

Factors with uncertain, controversial, or unproven effects on brain tumor risk:

  • Cell phone use
  • Other environmental factors: exposure to vinyl chloride, petroleum products, and certain chemicals has been linked with an increased risk of brain tumors in some studies but not in others.

Resource: Risk Factors for Brain and Spinal Cord Tumors | American Cancer Society

Brain Cancer Key Facts

  • Estimates of 80,000 brain tumors are diagnosed in the U.S. each year, and approximately 30% will be considered malignant – or cancerous
  • An estimated 24,740 malignant tumors of the brain and spinal cord will be diagnosed in the U.S. in 2026, with around 18,350 deaths expected.
  • Overall, the chance that a person will develop a malignant tumor of the brain or spinal cord in his or her lifetime is less than 1%. The risk is slightly higher for men than women.
  • Survival rates vary widely depending on the type of tumor
  • Glioblastoma (GBM) is the deadliest type of brain cancer, with a 5-year survival rate of 28% for ages under 39 and 6% for ages 40+.

Source: American Cancer Society’s Cancer Facts & Figures 2024; National Brain Tumor Society; Global Coalition for Adaptive Research

What NFCR is doing to address Brain Cancer

The NFCR-Supported and Past-Supported Researchers have programs that will prevent, detect and improve outcomes for brain cancer patients.

Select a research below to learn more about their specific work.

Dr. Rakesh K. Jain

Rakesh K. Jain, Ph.D.
Massachusetts General Hospital & Harvard Medical School

Paul Fisher, M.Ph., Ph.D.
Virginia Commonwealth University

Webster K. Cavenee, Ph. D.
Ludwig Institute for Cancer Research

Cesare Spadoni, Ph.D.
University of London

W. K. Alfred Yung, M.D.
University of Texas MD Anderson Cancer Center

Brain Cancer Awareness Month is recognized in May.