
Paul Macklin is a mathematician, Professor of Intelligent Systems Engineering, and Associate Dean for Undergraduate Education at the Luddy School of Informatics, Computing and Engineering at Indiana University. His lab develops the award-winning PhysiCell simulation framework as a “virtual laboratory” to study complex biological systems, with a special focus on cancer. As part of this work, he recently released a new modeling language that allows rapid development of simulation models that can be used to interactively explore the “rules” of cancer systems and run virtual experiments. He is working with teams of biologists, bioinformaticians, modelers, and clinicians to combine these tools with artificial intelligence for virtual clinical trials, and to create digital twins for the future of personalized predictive cancer medicine.










