Transformative Therapies
What is Transformative Therapies?
Transformative cancer therapies are groundbreaking treatment modalities that leverage novel biological mechanisms to improve therapeutic outcomes over standard-of-care regimens. These innovative approaches often exploit recent scientific discoveries to target cancer through distinct mechanisms.
Examples of transformative therapies include gene and viral therapies modifying genetic material, immunotherapies harnessing the immune system, targeted therapies against specific molecular drivers, and novel therapeutic platforms like antibody-drug conjugates. These cutting-edge treatments aim to overcome limitations of conventional cytotoxic chemotherapies.
NFCR IMPACTS IN TRANSFORMATIVE THERAPIES RESEARCH
- NFCR provides crucial funding for early-stage research into high-risk, high-reward transformative therapy concepts that may struggle to secure traditional funding.
- Through its translational research initiatives, NFCR supports the development of promising transformative therapies from laboratory discoveries to clinical applications.
- NFCR facilitates collaborations between researchers, clinicians, and industry partners to accelerate the development and testing of transformative therapies.
NFCR-Supported Researchers Working on Transformative Therapies
Yung-Chi Cheng, Ph.D.
Yale University
Katherine Uyhazi, M.D., Ph.D.
University of Pennsylvania Perelman School of Medicine
Tomas Aleman, M.D.
University of Pennsylvania Perelman School of Medicine
Susan Band Horwitz, Ph.D.
Albert Einstein College of Medicine
